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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYGB
All Species:
42.73
Human Site:
Y405
Identified Species:
85.45
UniProt:
P11216
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11216
NP_002853.2
843
96696
Y405
P
R
H
L
E
I
I
Y
A
I
N
Q
R
H
L
Chimpanzee
Pan troglodytes
XP_525293
1007
114448
Y569
P
R
H
L
E
I
I
Y
A
I
N
Q
R
H
L
Rhesus Macaque
Macaca mulatta
XP_001100555
843
96591
Y405
P
R
H
L
E
I
I
Y
A
I
N
Q
R
H
L
Dog
Lupus familis
XP_534201
809
92651
Y371
P
R
H
L
E
I
I
Y
A
I
N
Q
R
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI94
843
96711
Y405
P
R
H
L
E
I
I
Y
A
I
N
Q
R
H
L
Rat
Rattus norvegicus
P53534
838
96156
Y405
P
R
H
L
E
I
I
Y
A
I
N
Q
R
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026205
843
96712
Y405
P
R
H
L
E
I
I
Y
A
L
N
Q
M
H
L
Frog
Xenopus laevis
NP_001080170
843
96849
Y405
P
R
H
L
E
I
I
Y
A
I
N
Q
K
H
L
Zebra Danio
Brachydanio rerio
NP_997974
843
97409
Y405
P
R
H
L
Q
I
V
Y
E
I
N
R
R
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XTL9
844
96978
Y405
P
R
H
L
Q
I
I
Y
H
I
N
F
L
H
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SD76
841
95141
E406
P
R
H
M
E
I
I
E
E
I
D
K
R
F
V
Baker's Yeast
Sacchar. cerevisiae
P06738
902
103525
Y455
P
R
H
L
E
I
I
Y
D
I
N
W
F
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
99.1
90.9
N.A.
95.6
94.9
N.A.
N.A.
90.9
87.6
86.8
N.A.
72
N.A.
N.A.
N.A.
Protein Similarity:
100
83.7
99.6
94.1
N.A.
98.5
97.6
N.A.
N.A.
97
95.9
95.1
N.A.
86.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
93.3
73.3
N.A.
66.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
100
93.3
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.9
48.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.2
64.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% D
% Glu:
0
0
0
0
84
0
0
9
17
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
9
17
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
100
0
0
0
0
0
9
0
0
0
0
84
0
% H
% Ile:
0
0
0
0
0
100
92
0
0
92
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% K
% Leu:
0
0
0
92
0
0
0
0
0
9
0
0
9
0
84
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
92
0
0
0
0
% N
% Pro:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
0
67
0
0
0
% Q
% Arg:
0
100
0
0
0
0
0
0
0
0
0
9
67
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _